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Comparative Biomedical Sciences

The Field of Comparative Biomedical Sciences (CBS) provides students with the opportunity to pursue research at the number one College of Veterinary Medicine in the country (US News and World Report). Students can choose from among nearly 100 faculty mentors.  Faculty interests include cancer biology, development, reproductive biology, neuroscience, aging, microbiology, immunology, stem cell biology, genomics, and epidemiology. Graduate students in CBS include PhD, DVMs seeking PhDs, and combined degree (DVM/PhD) students. Students can pursue fundamental questions in basic research, or take advantages of interactions between clinicians and basic scientists to incorporate translational perspectives in their work. As a member of the Biomedical and Biological Sciences program, CBS is part of a vibrant graduate community in the Veterinary College.

Admission

CBS is a part of the Biological & Biomedical Sciences Graduate Program (BBS); applicants should follow the BBS application guidelines.  (Please note: CBS requires that two (2) letters of recommendation are submitted for an applicant.)

Faculty

Dorothy Ainsworth
Dorothy Ainsworth
Limitations of the respiratory system in health and in disease to equine athletic performance; pulmonary biology; immunology and inflammation

Craig Altier
Craig Altier

Molecular basis of Salmonella pathogenesis; the genetic and environmental control of epithelial cell invasion
Douglas Antczak
Douglas Antczak
Immunogenetics and infectious diseases
Judith A. Appleton, Ph.D.
Judith Appleton
Nematode parasites; parasitism; Trichinella spiralis; Paralaphostrongylus tenuis; mucosal immunity
baneux
Philippe Baneux

Encephalitozoon cuniculi; laboratory animal medicine, science and management; animal models of human disease including non-human primates; safety sciences (preclinical toxicology; GLP; GCP).

Stephen Barr
Stephen Barr

Pathogenesis of protozoal disease (Trypanosoma cruzi, Leishmania giardia); platelet function

Carl Batt
Carl Batt

Rapid diagnostic methods; molecular epidemiology

Rodrigo Bicalho
Rodrigo Bicalho

Postpartum uterine diseases of cows, specifically puerperal metritis, clinical and subclinical endometritis; bovine metritis as a model to study female urinary tract infection; epidemiology of lameness in dairy cattle (assessment of risk factors, prevalence, biomechanics of bovine digits and preventive/treatment strategies); factors affecting reproductive efficiency in dairy cows; development and implementation of analytical tools that will aid data driven decision making in dairy farms; discovery and development of novel antimicrobials

Blissard
Gary Blissard

Viral entry into insect host cells; viral gene expression

Dr. Dwight Bowman
Dwight Bowman

Parasitology

Adam Boyko
Adam Boyko

Genomic investigation of dogs as a model of genetic disease and evolutionary genetics
Nicolas Buchon
Nicolas Buchon
Host/Microbe relationships and Control of intestinal stem cell behavior in homeostasis and disease

Elizabeth Buckles
Elizabeth Buckles

Virology; population medicine; infectious diseases; disease diagnosis; wildlife disease; conservation biology; pathology; avian diseases

Jonathan Butcher
Jonathan Butcher

Mechanobiology of Development 

Elizabeth Bynoe
Margaret Bynoe

Cellular and molecular medicine; infectious diseases; molecular basis of antigen-induced immune suppression; the modulation of innate immune system response in immunity against cancer

Dr. Casey
James Casey

Molecular virology; retrovirology

Sharon Center
Sharon Center

Liver and kidney diseases of small animals

Richard Cerione
Richard Cerione

Biochemical and molecular pharmacology

Yung-Fu Chang
Yung-Fu Chang

Molecular genetics in the study of pathogenesis of bacterial disease
cheetham
Jonathan Cheetham
Peripheral nerve injury and repair. Laryngeal Function.

Theodore Clark
Theodore Clark

Cutaneous immunity; host-parasite interaction; DNA vaccines; genetic factors underlying resistance to infectious disease

Paula Cohen
Paula Cohen

Mammalion meiosis; germ cell development; DNA repair mechanisms in recombination; genetic basis for nondisjunction in oocytes; transgenic and knocko-t mouse models for studying meiosis and recombination

Ruth Collins
Ruth Collins

Regulation of membrane traffic by small GTP-ases

Bethany Cummings
Bethany Cummings

Obesity, insulin resistance and type 2 diabetes pathogenesis and treatment; Development and study of rodent models of bariatric surgery.

Scott Coonrod
Scott Coonrod

Developmental and reproductive biology; structural and functional biology

Charles Danko, Ph.D.
Charles Danko

Medical Genetics & Genomics and Cancer Biology Research

Matthew DeLisa
Matthew DeLisa

Molecular biotechnology; protein biogenesis and folding pathways; protein engineering

Edward Dubovi
Edward Dubovi

Virology; viral pathogenesis; BVD virus; EAV virus

picture of Norm Ducharme
Normand Ducharme

Equine sports medicine; upper respiratory tract

Gerald Duhamel
Gerald Duhamel

Molecular mechanisms of intestinal bacterial infections in animal models of human diseases, primarily polymicrobial associations in colitis and understanding host-pathogen interactions in the context of gut ecology

Maria Julia Bevilaqua Felippe
Julia Felippe

B cell response; neonatal and clinical immunology
Clare Fewtrrell
Clare Fewtrell
Cellular pharmacology; immediate hypersensitivity; immunopharmacology

Claudia Fischbach-Teschl
Claudia Fischbach-Teschl

Tissue-engineered model systems for analysis of microenvironmental conditions fundamental to cancer pathogenesis and therapy

picture of Dr. Lisa Fortier
Lisa Fortier

Osteoarthritis and the link between insulin-like growth factor-I and the small G-proteins, Cdc42, Rac, and Rho

Maria Garcia-Garcia
Maria Garcia-Garcia

Development biology in mice and flies; genetics of developmental mechanisms that influence embryonic morphology

Robin Gleed
Robin Gleed

Respiration; hypoxea and pulmonary circulation

Goldberg
Jesse Goldberg

Systems neuroscience, neural circuits, motor learning 

Yrjo Grohn
Yrjo Grohn

Epidemiology; dairy herd health; ruminant metabolism

Harrington, Laura C.
Laura Harrington

Vector borne diseases; epidemiology; vector biology physiology; mosquito-parasite interactions

Kei Hayashi
Kei Hayashi

Arthroscopy, total joint arthroplasty, biological approach to joint surgery, minimally invasive fracture treatment, and application of novel research discoveries (such as stem cell and regenerative medicine technologies) to clinical patients

Galina Hayes
Galina Hayes

Clinical epidemiology

Hu, Fenghua
Fenghua Hu

Molecular and cellular mechanisms of neurodegeneration

Kelly Hume
Kelly Hume

cancer biology, veterinary oncology, clinical oncology, molecular oncology, DNA damage, chemosensitivity, and novel therapeutics

Renata Ivanek Miojevic
Renata Ivanek

Dr. Katie Kelly
Kathleen Kelly

Epidemiology and ecology of infectious and foodborne diseases; Mathematical modeling; Spatial epidemiology; Risk assessment; Public Health

Pathophysiology of cardiovascular disease; effects of inflammation on cardiac function; comparative pathology     

Michael Kotlikoff
Michael Kotlikoff

Molecular and cellular physiology; physiological genomics

Natasza Kurpios
Natasza Kurpios

Study of signaling pathways that direct organogenesis of vertebrates to determine distinct cellular behaviors and cell shape during development

Jan Lammerding
Jan Lammerding

cellular biomechanics; mechanotransduction;  cell migration; muscular dystrophy and cancer cell biology

Brian Lazzaro
Brian Lazzaro

Evolutionary genetics of insect-pathogen interactions; population genetics and molecular evolution; quantitative genetics and genomics

Lee, Sylvia 2009
Sylvia Lee
Molecular genetics of aging; signaling pathways of nutrient sensing; molecular basis of stress response

Cynthia Leifer
Cynthia Leifer

Understanding innate immunity from the inside out; toll-like receptors; signaling; dendritic cells; controlling microbial infection

Roy Levine
Roy Levine

Developmental biology; growth control and cancer
libert
Sergiy Libert

Mice; molecular biology of aging, age-associated diseases, cancer, neurodegeneration; anorexia, energy metabolism

David Lin
David Lin

Mice; olfaction; genetics; neurobiology; development; microarrays; genomics
Sabine Mann
Sabine Mann

Metabolic diseases and insulin signaling; nutrition; epidemiology; metabolic and nutritional immunology

Dr. Hélène Marquis
Helene Marquis

Pathogenesis of Listeria monocytogenes; mechanisms of regulation of specific virulence factors; signaling during bacterial cell-to-cell spread
Martin
Mary Martin

Laboratory animal medicine, specifically the development of animal models to study mechanisms of disease; special interest in zoonotic diseases and pain management

Jessica McArt
Jessica McArt
Identification, epidemiology, and economics of periparturient diseases in dairy cattle

picture of Dr. Angela L. McCleary-Wheeler
Angela McCleary-Wheeler

Companion animal models of cancer; hedgehog signaling; epigenetics; novel therapeutics

McDonough
Sean McDonough

Use of contemporary methods to explore lymphocyte function in spontaneous veterinary deseases

Saurabh Mehta
Saurabh Mehta

Global Health (active research projects in India, East Africa, and Latin America); Infectious Disease Epidemiology, particularly HIV, Tuberculosis, and Neglected Tropical Diseases; Nutritional Interventions and Nutritional Modulation of the Immune Response 

Vicki Meyers-Wallen
Vicki Meyers-Wallen

Inherited canine diseases; reproductive tract disorders
Andrew Miller
Andrew Miller

Anatomic Pathology; small and large animal neuropathology; CNS tumorigenesis; disease diagnostics; stem cell pathology

Hussni Mohammed
Hussni Mohammed

Epidemiology of infectious diseases; production medicine

N. Sidney Moise
N. Sidney Moise

Arrhythmias; Sudden Death syndrome

Alexander Nikitin, MD, PhD
Alexander Nikitin

Genetic modeling of human cancer in the mouse; early detection and monitoring of carcinogenesis; neoplasms of reproductive and endocrine systems

Linda Nowak
Linda Nowak

Neurosciences; cellular physiology; receptor pharmacology; membrane biophysics

Daryl Van Nydam
Daryl Van Nydam

Epidemiology of food security/safety issues related to dairy production medicine; study of economically important infectious diseases, particularly zoonoses, subclinical diseases of periparturient cattle and reproductive efficiency

Robert Oswald
Robert Oswald

Ion channels; acetylcholine receptors

John S. L. Parker, BVMS, PhD
John Parker

Reoviruses; caliciviruses; virus structure; virus assembly; virus-host interactions; oncolytic viruses; virology

Colin Parrish, PhD
Colin Parrish

Viral genetics and function

Ned Place
Ned Place

Reproductive aging; physiology; endocrinology

Heidi Reesink
Heidi Reesink

Comparative and translational orthopedics; metabolism and musculoskeletal disease; osteoarthritis; regenerative medicine
Dr. Kristy Richards
Kristy Richards
Immuno-oncology, monoclonal antibodies, genetic mechanisms of resistance, personalized medicine, comparative oncogenomics, novel therapeutic development

Mark Roberson, PhD
Mark Roberson

Molecular endocrinology in reproductive tissues

Brain Rudd
Brian Rudd

Understanding developmental-related mechanisms limiting immunity in early life.

Dr. David Russell
David Russell

The biology of intracellular infection with emphasis on mycobacteria
Praveen Sethupathy
Praveen Sethupathy
Functional genomics, gene regulation, molecular genetics, gastrointestinal physiology, stem cell biology, metabolic disease

John Schimenti, PhD
John Schimenti

Mouse genetics and functional genomics, genomic instability, genetic recombination, genetics of gametogenesis and development, use of ES cells to mutagenize the mouse genome

picture of Kenneth W. Simpson
Kenneth Simpson

Gastroenterology

Paul Soloway, PhD
Paul Soloway

Epigenetic phenomena in mammals

Holger Sondermann
Holger Sondermann

Structural biology; cell signaling; biochemistry; biophysics

Dr. Jeongmin Song
Jeongmin Song

elucidating pathogenic mechanism(s) of Salmonella Typhi

Michael Stanhope
Michael Stanhope

Molecular evolution and comparative genomics of infectious disease organisms

Tracy Stokol
Tracy Stokol

Hematopoietic and hemostatic disorders in animals; mechanisms of cancer metastasis
Dr. Patrick Stover
Patrick Stover

investigating the fundamental mechanisms underlying the regulation of folate-mediated one-carbon metabolism and its role in mitochondrial and nuclear genome methylation and stability

Tudotira Tumbar
Tudotira Tumbar
basic cellular and molecular mechanisms implicated in cell fate choice and stem cell activity within tissues
Dr. Elia Wojno
Elia Tait Wojno
Exploring the immune system when it functions correctly and also when it malfunctions

Rory Todhunter
Rory Todhunter

Canine hip dysplasia; genetic linkage analysis; osteoarthritis

Alex Travis, VMD, PhD
Alexander Travis

Comparative biology of male germ cells; signaling and metabolism of sperm during capacitation; organization of lipid raft membrane sub-domains in sperm; applications of technologies using reproductive stem cells for wildlife conservation

Dr. Gerlinde Van de Walle
Gerlinde Van de Walle 

alphaherpesvirus pathogenesis, basic biology/immunology of mesencymal stem cells for regenerative therapy, Mammary gland stem cell biology and carcinogenesis.

Bettina Wagner
Bettina Wagner

Antibody mediated immune mechanisms in infectious disease and vaccination; allergic diseases; neonatal tolerance and allergy predisposition; strategies to develop allergy treatments

Joseph Wakshlag
Joseph Wakshlag

Exercise physiology and obesity metabolism; canine-cancer biology (mast cell and bone neoplasia) and the effects of nutrients and cellular metabolites on cell signaling

Lorin Warnick
Lorin Warnick

Dairy cattle epidemiology; pre-harvest food safety; Salmonellosis in cattle; infectious disease

Gregory Weiland
Gregory Weiland

Neuropharmacology; receptor mechanisms

Robert Weiss
Robert Weiss

Genomic maintenance mechanisms; cell cycle checkpoints; molecular responses to genomic stress; mouse models of genomic instability
Andrew C. White
Andrew C. White
Cancer biology; stem cell biology; biochemistry and cell biology

Dr. Gary Whittaker
Gary Whittaker

Virology cell biology; biochemistry

Martin Wiedmann
Martin Wiedmann

Molecular pathogenesis of food-borne and zoonotic bacterial diseases

Mariana Wolfner
Mariana Wolfner

Molecular and genetic mechanisms of reproductive processes. Specifically, functions and evolution of seminal proteins and (separately) mechanisms of egg activation and early embryogenesls

Chris Xu
Chris Xu

Optical imaging of neural structure and function

Andrew Yen
Andrew Yen

Leukemia; cell growth and differentiation; oncogenes/genetics

Cornelia Farnum
Cornelia Farnum (emeritus)

Functional anatomy of cartilage and bone

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