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Molecular and Integrative Physiology

The study of physiology covers a broad range of investigations under the umbrella of "how living organisms function."  The PhD program in Molecular and Integrative Physiology offers a comprehensive program of study and research opportunities emphasizing training in molecular/genomic aspects of cell, organ and whole animal physiology, with an emphasis on physiological genomics. The program of study provides an outstanding foundation in physiological mechanisms at the cellular, tissue, organ and whole animal level, and how these mechanisms interface with molecular and genetic aspects.

Students have the opportunity to concentrate in the following areas: reproductive physiology and genomics; cardiovascular physiological genomics; endocrinology; environmental and comparative physiology; gastrointestinal and metabolic physiological genomics; membrane and epithelial physiology; neural and sensory physiological genomics.

Admission

Since MIP is a part of the Biological & Biomedical Sciences Graduate Program (BBS), applicants to the Field should follow the BBS application guidelines. MIP requires two (2) letters of recommendation.

Faculty

Carolyn Adler
Carolyn Adler

Regeneration; stem cell biology; tissue homeostasis; transcriptional regulation of cell differentiation

Adkins-Regan
Elizabeth Adkins-Regan

Behavioral physiology; endrocrinology; reproductive physiology

Ainsworth
Dorothy Ainsworth
Cardiovascular and respiratory physiology
Douglas Antczak
Douglas Antczak
Cellular transport mechanisms and electrolyte regulation; NaCl secretion in renal tubules
Adam Boyko
Adam Boyko
Genetics of domestication and rapid adaptation; canine genomics; evolutionary and population genetics; bioinformatics
W. Ron Butler
W. Ron Butler
Reproductive physiology - gonadotropins and ovarian function; reproduction/nutrition interactions

Paula Cohen
Paula Cohen

Etiology of spontaneous birth defects in mammals; mechanisms of meiotic recombination; DNA repair proteins in meiosis and recombination; germ cell development; ovarian development

Scott Coonrod
Scott Coonrod

Reproductive physiology; molecular and cellular physiology; the role that novel, highly abundant and egg-restricted molecules play in epigenetic reprogramming during the egg-to-embryo transition; mechanisms by which specific histone modifications are dynamically regulated during hormone-dependent gene transcription in breast cancer cells

Bethany Cummings
Bethany Cummings

Obesity, insulin resistance and type 2 diabetes pathogenesis and treatment; development and study of rodent models of bariatric surgery

Robin Dando
Robin Dando

Behavioral physiology; molecular and cellular physiology; neural and sensory physiology; physiological genomics; neurotransmitter interactions and signaling events which occur within the taste system
Scott Emr
Scott Emr
Regulation of cell signaling and membrane trafficking pathways by phosphoinositide kinases; protein kinases; ubiquitin modifications; vesicle-mediated transport reactions
Claudia Fishbach-Teschl
Claudia Fischbach-Teschl
Tissue-engineered model systems for analysis of microenvironmental conditions fundamental to cancer pathogenesis and therapy
Maria Garcia-Garcia
Maria Garcia-Garcia
Developmental biology in mice and flies; genetics of development mechanisms that influence embryonic morphology
Cole Gilbert
Cole Gilbert
Neural mechanisms of behavior in arthropods
Robin Gleed
Robin Gleed
Respiration, hypoxea, and pulmonary circulation; anesthesiology
Harris Warrick
Ron Harris-Warrick
Cellular and synaptic mechanisms that shape network function and motor output from Central Pattern Generator circuits
Patricia Johnson
Patricia Johnson
Endocrinology; reproductive physiology
Michael Kotlikoff
Michael Kotlikoff
Cardiovascular and respiratory physiology; molecular and cellular physiology

Natasza Kurpios
Natasza Kurpios

Study of signaling pathways that direct organogenesis of vertebrates to determine distinct cellular behaviors and cell shape during development
Cynthia Leifer
Cynthia Leifer
Regulation of innate immune receptors such as Toll-like receptors (TLRs); role of TLRs in autoimmunity, initiation of inflammatory responses to microbial infection, development of molecular and cellular, as well as whole animal models to study the biology of TLRs
libert
Sergiy Libert
Mice; molecular biology of aging; age-associated diseases; cancer; neurodegeneration; anorexia; energy metabolism
David Lin
David Lin
Axon guidance and target formation during the development of the mouse olfactory system, using genetic, in vitro, and genomic approaches
Ellis Loew
Ellis Loew
Physiology of vision; sensory biophysics; sensory ecology and nutritional ophthalmology
Marla Lujan
Marla Lujan
Nutritional regulations of female reproduction

Vicki Meyers-Wallen
Vicki Meyers-Wallen

Developmental biology; genetics; reproductive biology

Alexander Nikitin, MD, PhD
Alexander Nikitin

Genetic modeling of human cancer in the mouse; early detection and monitoring of carcinogenesis; neoplasms of reproductive and endocrine systems

Linda Nowak
Linda Nowak

Membrane biophysics; molecular biology of glutamate receptors; cellular neurophysiology; pharmacology of synaptic transmission
Kimberly O'Brien
Kimberly O'Brien
Calcium metabolism and bone health; control of maternal/fetal nutrient; partitioning and cellular mineral transport; micronutrient status in international settings; development of mass spectrometric methodology; pediatric bone health; pregnancy and mineral metabolism in adolescents

Ned Place
Ned Place

Mammalian reproductive biology with a focus on the life history of trade-offs associated with timing of hormone secretion and reproductive effort; sexual differentiation
Shu-Bing Qian
Shu-Bing Qian
Nutrient signaling pathway, stress response, protein synthesis, and their implications on human disease

Susan Quirk
Susan Quirk

Reproductive physiology; focus on molecular and cellular aspects of ovarian function

Mark Roberson, PhD
Mark Roberson

Reproductive physiology; endocrinology; molecular and cellular physiology
Chris Schaffer
Chris Schaffer
Advanced optical techniques used to observe and manipulate in vivo biological systems with the goal of developing microscopic scale understanding of normal and disease-state physiological processes

John Schimenti, PhD
John Schimenti

Molecular and cellular physiology; physiological genomics; reproductive physiology; mouse genetics and functional genomics; genomic instability; genetic recombination; genetics of gometogenesis and development; use of ES cells to mutagenize the mouse genome
selveraj
Vimal Selvaraj
Mammalian reproductive physiology; stem cells; technologies for wildlife conservation

Carolyn Sevier
Carolyn Sevier

Characterization of the signaling pathways that sens and respond to cellular redox imbalances to alleviate oxidative stress

Alex Travis, VMD, PhD
Alexander Travis

Biology of male germ cells; signaling and metabolism of sperm during capacitation; organization of lipid raft subdomains in sperm; conservation applications of germ cell reproductive technologies
Robert Weiss
Robert Weiss
Genomic maintenance mechanisms; cell cycle checkpoints; molecular responses to genomic stress; mouse models of genomic instability

Mariana Wolfner
Mariana Wolfner

Molecular and genetic mechanisms of reproductive processes, specifically, functions and evolution of seminal proteins and (separately) mechanisms of egg activation and early embryogenesls

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