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Elia Tait Wojno, PhD

Dr. Elia Wojno

Department of Microbiology and Immunology

Baker Institute for Animal Health

Assistant Professor of Microbiology and Immunology

Baker Institute for Animal Health


Baker Institute for Animal Health
235 Hungerford Hill Road
Ithaca, NY 14853

Department of Microbiology and Immunology
Cornell University College of Veterinary Medicine
C5 171 Veterinary Medical Center
Ithaca, NY 14853


Office: 607.253.3400
Email: edt42@cornell.edu

Research Interest

Allergies: How the immune system can make your pet miserable
Dr. Elia Tait Wojno explores the immune system when it functions correctly (to eliminate parasites) and also when it malfunctions (resulting in allergic disease).

  • Similarities between dog and human allergies. Tait Wojno and her team have studied blood samples from dozens of canine patients at the Cornell University Hospital for Animals, including dogs with skin itching, redness, rashes, and other allergic signs, and dogs without allergies. They found that allergic dogs have a specific type of immune cell in their blood, cells also found in allergic humans and mice. The discovery means that human treatments for these types of allergic signs could also work in canine medicine. 
  • Studying how lipids and proteins affect inflammation during infection and allergy. Tait Wojno is exploring how the oily molecules called lipids and other protein molecules called cytokines affect the process of inflammation. Inflammation causes some of the signs and symptoms of allergic disease but helps the body fight infection with parasitic worms. Understanding how lipids and cytokines work to control inflammation will inform the development of new drugs that target these factors to treat allergies or fight parasitic infections. 
  • Exploring how the immune system develops. In collaboration with scientists here at Cornell and at the University of Rochester, Tait Wojno’s laboratory has begun studying how the cells of the immune system develop over a lifetime and what happens to make it all work correctly in animals and humans of different ages.

Education

  • January 2011: Ph.D., University of Pennsylvania, Philadelphia, PA. Biomedical Graduate Studies, Cell and Molecular Biology Graduate Group, Microbiology, Virology, and Parasitology Program
  • May 2005: B.A., Drew University, Madison, NJ. Biology major. GPA 3.931 overall, major 3.945, graduation with honors

Biography/Professional Experience

  • January 2004 - 2005: Student Researcher, Drew University, Madison, NY. Drug resistance in parasitic nematodes. William Campbell, Ph.D, Advisor.
  • September 2005 - December 2010: Ph.D. Student, University of Pennsylvania, Philadelphia, PA. Laboratory of Christopher Hunter, Ph.D. Immune responses during infection with Toxoplasma gondii and the function of IL-27 during Toxoplasma gondii infection and in T regulatory cell homeostasis.
  • January 2011 - June 2011: Postdoctoral Fellow, University of Pennsylvania, Philadelphia, PA. Laboratory of Christopher Hunter, Ph.D.
  • June 2011 - December 2014: Postdoctoral Fellow, University of Pennsylvania, Philadelphia, PA and Weill Cornell Medical College, Cornell University, New York, NY. Laboratory of David Artis, Ph.D.
  • January 2015 - present: Assistant Professor, Cornell University, College of Veterinary Medicine, Baker Institute for Animal Health, Department of Microbiology and Immunology, Ithaca, NY. Dissecting the contribution of innate immune cells, prostaglandins, and epithelial cell-derived cytokines to T helper type 2 cytokine-mediated inflammation at mucosal sites.

Selected Publications

Links and abstracts for all of Dr. Tait Wojno's publications can be found at NCBI.

1. Tait Wojno, ED; Artis, D. (2016). Emerging concepts and future challenges in innate lymphoid cell biology.  The Journal of Experimental Medicine, 213(11), 2229-2248. 

2. Monticelli, LA; Buck, MD; Flamar, AL; Saenz, SA; Tait Wojno, ED; Yudanin, NA; Osborne, LC; Hepworth, MR; Tran, SV; Rodewald, HR; Shah, H; Cross, JR; Diamond, JM; Cantu, E; Christie, JD; Pearce, EL; Artis,D. (2016). Arginase 1 is an innate lymphoid cell-intrinsic metabolic checkpoint controlling type 2 inflammation.  Nature Immunology, 17(6):656-665.

3. Tait Wojno, ED. (2016). Innate lymphoid cells: an emerging population in type 2 inflammation.  WC Gause & D Artis (Eds.), The Th2 Type Immune Response (pp. 13-31)New York, NY: Springer.

4. Tait Wojno, ED; Monticelli, LA; Tran, SV; Alenghat, T; Osborne, LC; Thome, JJ; Willis, C; Budelsky, A; Farber, DL; Artis, D. (2015). The prostaglandin D22 receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lungMucosal Immunology, 8(6), 1313-1323.  

5. Kim, BS; Wang, K; Siracusa, MC; Saenz, SA; Brestoff, JR; Monticelli, LA; Noti, M; Tait Wojno, ED; Fund, TC; Kubo, M; Artis, D. (2014).  Basophils promote innate lymphoid cell responses in inflamed skin Journal of Immunology, 193(7), 3717-3725.

6. Siracusa, MC; Saenz, SA; Tait Wojno, ED; Kim, BS; Osborne, LC; Ziegler, CG; Benitez, AJ; Ruymann, KR; Farber, DL; Sleiman, PM; Hakonarson,H; Cianferoni, A; Wang, ML; Spergel, JM; Comeau, MR; Artis, D. (2013).  Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.  Immunity, 39(6), 1158-1170.

7. Tait Wojno, ED;*, Noti, M;*, Kim, BS; Siracusa, MC; Giacomin, PR; Nair, MG; Benitez, AJ; Ruymann, KR; Muir, AB; Hill, DA; Chikwava, KR; Moghaddam, AE; Sattentau, QJ; Alex, A; Zhou, C; Yearley, JH; Menard-Katcher, P; Kubo, M; Obata-Ninomiya, K; Karasuyama, H; Comeau, MR; Brown-Whitehorn, T; Malefyt, R; Sleiman, PM; Hakonarson, AC; Falk, GW; Wang, ML; Spergel, JM; Artis, D.  (2013).  TSLP-elicited basophil responses promote eosinophilic esophagitisNature Medicine, 19(8), 1005-1013.  * These authors contributed equally.

Awards and Honors

  • American Association of Immunologists, Early Career Faculty Travel Grant, May 2015
  • Woods Hole Immunoparasitology Conference, Parasite Immunology Woods Hole Immunoparasitology Poster Prize, April 2015
  • American Association of Immunologists, Trainee Abstract Award, May 2014
  • International Cytokine and Interferon Society Postdoctoral Investigator Award, First Place, September 2013 
  • Novartis Award in Biology, Spring 2005 
  • Beta Beta Beta Convention Brooks Award, Spring 2005 
  • Phi Beta Kappa, inducted Spring 2004
  • Drew Scholars Award, Fall 2001

Professional/Academic Affiliations

  • Participant, American Association of Immunologists Membership Focus Group. May 2015
  • Primary Member, Cornell University College of Veterinary Medicine Graduate Field of Immunology and Infectious Disease. April 2015
  • Member, Cornell University College of Veterinary Medicine Graduate Field of Comparative Biomedical Sciences. April 2015. Reviewer, Infection and Immunity, April 2015

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